MolNFT v1 · #262975 · protein
AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase NEK3 (Q6ZEZ5)
Q6ZEZ5: “AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase NEK3 (Q6ZEZ5)”. 3 pockets (best druggability 0.73). MolNFT v1 #262975 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q6ZEZ5
- Type
- protein
- Length
- 585 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6Ed09D80e98fE15DE51C9E7a8896AbF1f2365C3e
- Molecule
- SERINE/THREONINE-protein kinase NEK3
- UniProt
- Q6ZEZ5
- Pockets
- 3 · best druggability 0.73
Structure
1 distinct chain · 28% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SERINE/THREONINE-protein kinase NEK3 | protein | 585 | 28% helix, 9% strand | Q6ZEZ5 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 914 | 0.73 | 0.77 | 84 | empty |
| 2 | 278 | 0.60 | 0.78 | 31 | empty |
| 3 | 93 | 0.36 | 0.75 | 18 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6ZEZ5
- Elsewhere: UniProt Q6ZEZ5 · AlphaFold DB Q6ZEZ5
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