MolNFT v1 · #262968 · protein
AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase NEK2 (O35942)
O35942: “AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase NEK2 (O35942)”. 5 pockets (best druggability 0.75). MolNFT v1 #262968 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O35942
- Type
- protein
- Length
- 443 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xB84ca8Ff15f9C376eed6FE9eE35ed4DE21CD886A
- Molecule
- SERINE/THREONINE-protein kinase NEK2
- UniProt
- O35942
- Pockets
- 5 · best druggability 0.75
Structure
1 distinct chain · 52% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SERINE/THREONINE-protein kinase NEK2 | protein | 443 | 52% helix, 11% strand | O35942 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 637 | 0.75 | 0.81 | 66 | empty |
| 2 | 134 | 0.46 | 0.77 | 23 | empty |
| 3 | 147 | 0.42 | 0.75 | 26 | empty |
| 4 | 53 | 0.37 | 0.79 | 9 | empty |
| 5 | 54 | 0.28 | 0.74 | 10 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O35942
- Elsewhere: UniProt O35942 · AlphaFold DB O35942
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