MolNFT v1 · #262905 · protein

AlphaFold monomer V2.0 prediction for nectin-3 (Q9NQS3)

Q9NQS3: “AlphaFold monomer V2.0 prediction for nectin-3 (Q9NQS3)”. 2 pockets (best druggability 0.52). MolNFT v1 #262905 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q9NQS3
Type: protein
Length: 549 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xfd2dFEa4905a57464111Bb0e4Cc483225AEe8a69
Molecule: Nectin-3
UniProt: Q9NQS3
Pockets: 2 · best druggability 0.52

Structure

1 distinct chain · 11% helix, 33% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nectin-3	protein	549	11% helix, 33% strand	Q9NQS3

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	314	0.52	0.74	35	empty
2	62	0.26	0.72	14	empty

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

4FOM · Crystal structure of human nectin-3 full ectodomain (D1-D3) · an experimental structure of the same protein · chain A against A, TM-score 0.54
4FOM · Crystal structure of human nectin-3 full ectodomain (D1-D3) · an experimental structure of the same protein · chain A against A, TM-score 0.54

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9NQS3
Elsewhere: UniProt Q9NQS3 · AlphaFold DB Q9NQS3

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