AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (Q8HXG6)

Structure

1 distinct chain · 79% helix, 0% strand (DSSP).

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

• 7R42 · Bovine complex I in the presence of IM1761092, active class ii (Composite map) · an experimental structure of the same protein · chain A against Y, TM-score 0.99
• 7R47 · Bovine complex I in the presence of IM1761092, deactive class iii (Composite map) · an experimental structure of the same protein · chain A against Y, TM-score 0.98
• 7R4D · Bovine complex I in the presence of IM1761092, deactive class vi (Composite map) · an experimental structure of the same protein · chain A against Y, TM-score 0.98
• 7QSM · Bovine complex I in lipid nanodisc, Deactive-ligand (composite) · an experimental structure of the same protein · chain A against Y, TM-score 0.98
• 7QSM · Bovine complex I in lipid nanodisc, deactive-ligand (composite) · an experimental structure of the same protein · chain A against Y, TM-score 0.98
• 7R45 · Bovine complex I in the presence of IM1761092, deactive class i (Composite map) · an experimental structure of the same protein · chain A against Y, TM-score 0.98
• 7R48 · Bovine complex I in the presence of IM1761092, deactive class iv (Composite map) · an experimental structure of the same protein · chain A against Y, TM-score 0.98
• 7R4C · Bovine complex I in the presence of IM1761092, deactive class v (Composite map) · an experimental structure of the same protein · chain A against Y, TM-score 0.98
• 7R41 · Bovine complex I in the presence of IM1761092, active class i (Composite map) · an experimental structure of the same protein · chain A against Y, TM-score 0.98
• 8Q46 · Inward-facing, open2 proteoliposome complex I at 2.6 A. Initially purified in LMNG. · an experimental structure of the same protein · chain A against Y, TM-score 0.98
• 8Q48 · Outward-facing, closed proteoliposome complex I at 2.5 A. Initially purified in LMNG. · an experimental structure of the same protein · chain A against Y, TM-score 0.98
• 7QSK · Bovine complex I in lipid nanodisc, active-Q10 · an experimental structure of the same protein · chain A against Y, TM-score 0.98

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q8HXG6
• Elsewhere: UniProt Q8HXG6 · AlphaFold DB Q8HXG6