MolNFT v1 · #262387 · protein
AlphaFold monomer V2.0 prediction for bifunctional heparan sulfate N-DEACETYLASE/N-sulfotransferase 2 (P52850)
P52850: “AlphaFold monomer V2.0 prediction for bifunctional heparan sulfate N-DEACETYLASE/N-sulfotransferase 2 (P52850)”. 12 pockets (best druggability 0.72). MolNFT v1 #262387 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P52850
- Type
- protein
- Length
- 883 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x0D671490EE06E75975e90D7F99F73B20BE618744
- Molecule
- Bifunctional heparan sulfate N-DEACETYLASE/N-sulfotransferase 2
- UniProt
- P52850
- Pockets
- 12 · best druggability 0.72
Structure
1 distinct chain · 41% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Bifunctional heparan sulfate N-DEACETYLASE/N-sulfotransferase 2 | protein | 883 | 41% helix, 17% strand | P52850 |
Pockets
12 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 493 | 0.72 | 0.81 | 52 | empty |
| 2 | 318 | 0.61 | 0.78 | 45 | empty |
| 3 | 266 | 0.55 | 0.76 | 37 | empty |
| 4 | 130 | 0.46 | 0.78 | 28 | empty |
| 5 | 94 | 0.43 | 0.79 | 20 | empty |
Modifications
Observed in the structure: 3 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P52850
- Elsewhere: UniProt P52850 · AlphaFold DB P52850
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