MolNFT v1 · #262361 · protein
AlphaFold monomer V2.0 prediction for protein NDRG3 (Q9UGV2)
Q9UGV2: “AlphaFold monomer V2.0 prediction for protein NDRG3 (Q9UGV2)”. 4 pockets (best druggability 0.52). MolNFT v1 #262361 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9UGV2
- Type
- protein
- Length
- 375 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x80DFF74473FD79110bd730F367842ad5E57E8738
- Molecule
- Protein NDRG3
- UniProt
- Q9UGV2
- Pockets
- 4 · best druggability 0.52
Structure
1 distinct chain · 35% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein NDRG3 | protein | 375 | 35% helix, 14% strand | Q9UGV2 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 219 | 0.52 | 0.77 | 32 | empty |
| 2 | 137 | 0.48 | 0.78 | 27 | empty |
| 3 | 61 | 0.32 | 0.76 | 12 | empty |
| 4 | 54 | 0.26 | 0.73 | 10 | empty |
Compared structures
- 6L4H · Crystal structure of human NDRG3 C30S mutant · an experimental structure of the same protein · chain A against A, TM-score 0.75
- 6L4H · Crystal structure of human NDRG3 C30S mutant · an experimental structure of the same protein · chain A against A, TM-score 0.75
- 6L4B · Crystal structure of human WT NDRG3 · an experimental structure of the same protein · chain A against B, TM-score 0.74
- 6L4B · Crystal structure of human wt NDRG3 · an experimental structure of the same protein · chain A against A, TM-score 0.74
- 6L4G · Crystal structure of human NDRG3 I171M/S176H mutant · an experimental structure of the same protein · chain A against B, TM-score 0.74
- 6L4G · Crystal structure of human NDRG3 I171M/S176H mutant · an experimental structure of the same protein · chain A against B, TM-score 0.74
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UGV2
- Elsewhere: UniProt Q9UGV2 · AlphaFold DB Q9UGV2
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