MolNFT v1 · #261488 · protein

AlphaFold monomer V2.0 prediction for nucleoside diphosphate kinase, mitochondrial (O00746)

O00746: “AlphaFold monomer V2.0 prediction for nucleoside diphosphate kinase, mitochondrial (O00746)”. 2 pockets (best druggability 0.51). MolNFT v1 #261488 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: O00746
Type: protein
Length: 187 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xA07F8d9D68124FDddD657b6fFA18449239Fb32Da
Molecule: Nucleoside diphosphate kinase, mitochondrial
UniProt: O00746
Pockets: 2 · best druggability 0.51

Structure

1 distinct chain · 37% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nucleoside diphosphate kinase, mitochondrial	protein	187	37% helix, 13% strand	O00746

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	246	0.51	0.75	27	empty
2	76	0.46	0.82	21	empty

Compared structures

1EHW · Human nucleoside diphosphate kinase 4 · an experimental structure of the same protein · chain A against B, TM-score 0.75
1EHW · Human nucleoside diphosphate kinase 4 · an experimental structure of the same protein · chain A against B, TM-score 0.75

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O00746
Elsewhere: UniProt O00746 · AlphaFold DB O00746

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