MolNFT v1 · #260518 · protein

AlphaFold monomer V2.0 prediction for nucleoporin NDC1 (Q6AX31)

Q6AX31: “AlphaFold monomer V2.0 prediction for nucleoporin NDC1 (Q6AX31)”. 8 pockets (best druggability 0.54). MolNFT v1 #260518 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q6AX31
Type: protein
Length: 660 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x0D671490EE06E75975e90D7F99F73B20BE618744
Molecule: Nucleoporin NDC1
UniProt: Q6AX31
Pockets: 8 · best druggability 0.54

Structure

1 distinct chain · 60% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nucleoporin NDC1	protein	660	60% helix, 2% strand	Q6AX31

Pockets

8 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	297	0.54	0.75	35	empty
2	200	0.51	0.77	26	empty
3	101	0.44	0.78	22	empty
4	103	0.43	0.77	18	empty
5	136	0.41	0.74	20	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

7WKK · Cryo-EM structure of the ir subunit from X. laevis npc · an experimental structure of the same protein · chain A against N, TM-score 0.63
7WKK · Cryo-EM structure of the IR subunit from X. laevis NPC · an experimental structure of the same protein · chain A against N, TM-score 0.63

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6AX31
Elsewhere: UniProt Q6AX31 · AlphaFold DB Q6AX31

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