MolNFT v1 · #260315 · protein
AlphaFold monomer V2.0 prediction for NADPH--cytochrome P450 reductase (P04175)
P04175: “AlphaFold monomer V2.0 prediction for NADPH--cytochrome P450 reductase (P04175)”. 6 pockets (best druggability 0.86). MolNFT v1 #260315 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P04175
- Type
- protein
- Length
- 678 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xDbB2f4f08BfF33e6E02Dc57ac14F6FA31fCF4899
- Molecule
- NADPH--cytochrome P450 reductase
- UniProt
- P04175
- Pockets
- 6 · best druggability 0.86
Structure
1 distinct chain · 36% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NADPH--cytochrome P450 reductase | protein | 678 | 36% helix, 19% strand | P04175 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1106 | 0.86 | 0.87 | 127 | empty |
| 2 | 122 | 0.64 | 0.88 | 28 | empty |
| 3 | 141 | 0.54 | 0.81 | 26 | empty |
| 4 | 59 | 0.49 | 0.86 | 20 | empty |
| 5 | 53 | 0.45 | 0.84 | 15 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P04175
- Elsewhere: UniProt P04175 · AlphaFold DB P04175
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