MolNFT v1 · #260166 · protein
AlphaFold monomer V2.0 prediction for mitochondrial SODIUM/CALCIUM exchanger protein (F1NXU8)
F1NXU8: “AlphaFold monomer V2.0 prediction for mitochondrial SODIUM/CALCIUM exchanger protein (F1NXU8)”. 7 pockets (best druggability 0.80). MolNFT v1 #260166 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- F1NXU8
- Type
- protein
- Length
- 593 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xB44F19a0cb161828322eEEd13F55d4C3C34938d2
- Molecule
- Mitochondrial SODIUM/CALCIUM exchanger protein
- UniProt
- F1NXU8
- Pockets
- 7 · best druggability 0.80
Structure
1 distinct chain · 68% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mitochondrial SODIUM/CALCIUM exchanger protein | protein | 593 | 68% helix, 2% strand | F1NXU8 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 479 | 0.80 | 0.87 | 63 | empty |
| 2 | 307 | 0.74 | 0.86 | 39 | empty |
| 3 | 124 | 0.57 | 0.83 | 24 | empty |
| 4 | 227 | 0.53 | 0.77 | 34 | empty |
| 5 | 79 | 0.36 | 0.76 | 17 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt F1NXU8
- Elsewhere: UniProt F1NXU8 · AlphaFold DB F1NXU8
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