MolNFT v1 · #260149 · protein
AlphaFold monomer V2.0 prediction for SODIUM/POTASSIUM/CALCIUM exchanger 5 (Q49SH1)
Q49SH1: “AlphaFold monomer V2.0 prediction for SODIUM/POTASSIUM/CALCIUM exchanger 5 (Q49SH1)”. 5 pockets (best druggability 0.67). MolNFT v1 #260149 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q49SH1
- Type
- protein
- Length
- 513 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9120a2cD2BC3Db8eeBDF77645885D2Bcf135A1a5
- Molecule
- SODIUM/POTASSIUM/CALCIUM exchanger 5
- UniProt
- Q49SH1
- Pockets
- 5 · best druggability 0.67
Structure
1 distinct chain · 68% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SODIUM/POTASSIUM/CALCIUM exchanger 5 | protein | 513 | 68% helix, 2% strand | Q49SH1 |
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 387 | 0.67 | 0.80 | 50 | empty |
| 2 | 531 | 0.61 | 0.74 | 43 | empty |
| 3 | 436 | 0.59 | 0.75 | 47 | empty |
| 4 | 65 | 0.35 | 0.77 | 12 | empty |
| 5 | 77 | 0.31 | 0.73 | 16 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q49SH1
- Elsewhere: UniProt Q49SH1 · AlphaFold DB Q49SH1
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