MolNFT v1 · #260142 · protein
AlphaFold monomer V2.0 prediction for SODIUM/POTASSIUM/CALCIUM exchanger 2 (Q9UI40)
Q9UI40: “AlphaFold monomer V2.0 prediction for SODIUM/POTASSIUM/CALCIUM exchanger 2 (Q9UI40)”. 9 pockets (best druggability 0.71). MolNFT v1 #260142 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9UI40
- Type
- protein
- Length
- 661 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x1431f8f2D8A0757F2EEF7D9a43c9edC067005BE8
- Molecule
- SODIUM/POTASSIUM/CALCIUM exchanger 2
- UniProt
- Q9UI40
- Pockets
- 9 · best druggability 0.71
Structure
1 distinct chain · 60% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SODIUM/POTASSIUM/CALCIUM exchanger 2 | protein | 661 | 60% helix, 1% strand | Q9UI40 |
Pockets
9 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 355 | 0.71 | 0.83 | 46 | empty |
| 2 | 289 | 0.63 | 0.81 | 38 | empty |
| 3 | 364 | 0.56 | 0.74 | 36 | empty |
| 4 | 194 | 0.56 | 0.80 | 43 | empty |
| 5 | 53 | 0.41 | 0.82 | 14 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UI40
- Elsewhere: UniProt Q9UI40 · AlphaFold DB Q9UI40
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