MolNFT v1 · #260139 · protein
AlphaFold monomer V2.0 prediction for SODIUM/POTASSIUM/CALCIUM exchanger 1 (O60721)
O60721: “AlphaFold monomer V2.0 prediction for SODIUM/POTASSIUM/CALCIUM exchanger 1 (O60721)”. 5 pockets (best druggability 0.76). MolNFT v1 #260139 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O60721
- Type
- protein
- Length
- 1,099 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9073C46348542FfE4327c3F363F9B51B22058e75
- Molecule
- SODIUM/POTASSIUM/CALCIUM exchanger 1
- UniProt
- O60721
- Pockets
- 5 · best druggability 0.76
Structure
1 distinct chain · 37% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SODIUM/POTASSIUM/CALCIUM exchanger 1 | protein | 1099 | 37% helix, 1% strand | O60721 |
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1193 | 0.76 | 0.78 | 79 | empty |
| 2 | 540 | 0.71 | 0.80 | 54 | empty |
| 3 | 307 | 0.53 | 0.74 | 33 | empty |
| 4 | 70 | 0.44 | 0.81 | 13 | empty |
| 5 | 88 | 0.34 | 0.73 | 16 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O60721
- Elsewhere: UniProt O60721 · AlphaFold DB O60721
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