MolNFT v1 · #259634 · protein

AlphaFold monomer V2.0 prediction for nuclear autoantigenic sperm protein (P49321)

P49321: “AlphaFold monomer V2.0 prediction for nuclear autoantigenic sperm protein (P49321)”. 4 pockets (best druggability 0.42). MolNFT v1 #259634 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P49321
Type: protein
Length: 788 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x5c4adF1416281C09AE8eE1cbb80fF7e44cE86F97
Molecule: Nuclear autoantigenic sperm protein
UniProt: P49321
Pockets: 4 · best druggability 0.42

Structure

1 distinct chain · 30% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nuclear autoantigenic sperm protein	protein	788	30% helix, 0% strand	P49321

Pockets

4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	158	0.42	0.74	22	empty
2	70	0.36	0.77	11	empty
3	94	0.30	0.72	14	empty
4	60	0.29	0.74	16	empty

Compared structures

7V6Q · Crystal structure of snasp-ASF1A-H3.1-H4 complex · an experimental structure of the same protein · chain A against D, TM-score 0.27
7V6P · Crystal structure of human snasp tpr domain · an experimental structure of the same protein · chain A against A, TM-score 0.24

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P49321
Elsewhere: UniProt P49321 · AlphaFold DB P49321

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