MolNFT v1 · #256234 · protein
AlphaFold monomer V2.0 prediction for SODIUM/CALCIUM exchanger 3 (P57103)
P57103: “AlphaFold monomer V2.0 prediction for SODIUM/CALCIUM exchanger 3 (P57103)”. 12 pockets (best druggability 0.75). MolNFT v1 #256234 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P57103
- Type
- protein
- Length
- 927 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xa7e3031c43CB89a6785102a309F7e2b2e7370dBe
- Molecule
- SODIUM/CALCIUM exchanger 3
- UniProt
- P57103
- Pockets
- 12 · best druggability 0.75
Structure
1 distinct chain · 48% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SODIUM/CALCIUM exchanger 3 | protein | 927 | 48% helix, 16% strand | P57103 |
Pockets
12 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 400 | 0.75 | 0.85 | 45 | empty |
| 2 | 421 | 0.68 | 0.80 | 53 | empty |
| 3 | 80 | 0.56 | 0.87 | 16 | empty |
| 4 | 81 | 0.56 | 0.87 | 21 | empty |
| 5 | 321 | 0.53 | 0.73 | 34 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P57103
- Elsewhere: UniProt P57103 · AlphaFold DB P57103
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