MolNFT v1 · #255628 · protein

AlphaFold monomer V2.0 prediction for unconventional myosin-viia (P97479)

P97479: “AlphaFold monomer V2.0 prediction for unconventional myosin-viia (P97479)”. 20 pockets (best druggability 0.79). MolNFT v1 #255628 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P97479
Type: protein
Length: 2,215 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x9B130d619fCFc21d0D08E5Ce38Cf42A5fbe230CB
Molecule: Unconventional myosin-viia
UniProt: P97479
Pockets: 20 · best druggability 0.79

Structure

1 distinct chain · 49% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Unconventional myosin-viia	protein	2215	49% helix, 14% strand	P97479

Pockets

20 pockets found on a 1 Å grid, 13 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	938	0.79	0.81	83	empty
2	773	0.77	0.81	70	empty
3	930	0.76	0.79	97	empty
4	50	0.71	0.98	18	empty
5	411	0.70	0.81	31	empty

Compared structures

5WSU · Crystal structure of myosin viia IQ5-sah in complex with apo-cam · an experimental structure of the same protein · chain A against C, TM-score 0.03
5WST · Crystal structure of MYO7A sah · an experimental structure of the same protein · chain A against B, TM-score 0.03
5WSV · Crystal structure of myosin viia IQ5 in complex with CA2+-cam · an experimental structure of the same protein · chain A against B, TM-score 0.01

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P97479
Elsewhere: UniProt P97479 · AlphaFold DB P97479

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