MolNFT v1 · #255618 · protein

AlphaFold monomer V2.0 prediction for myosin-6 (Q9LKB9)

Q9LKB9: “AlphaFold monomer V2.0 prediction for myosin-6 (Q9LKB9)”. 8 pockets (best druggability 0.80). MolNFT v1 #255618 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q9LKB9
Type: protein
Length: 1,505 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xa6D533dDeEB1DAde828e7Cc2ca20af4B56132a5C
Molecule: Myosin-6
UniProt: Q9LKB9
Pockets: 8 · best druggability 0.80

Structure

1 distinct chain · 58% helix, 9% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Myosin-6	protein	1505	58% helix, 9% strand	Q9LKB9

Pockets

8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1051	0.80	0.81	129	empty
2	1001	0.76	0.78	106	empty
3	203	0.53	0.78	27	empty
4	73	0.48	0.83	19	empty
5	72	0.34	0.76	16	empty

Compared structures

7DHW · Crystal structure of myosin-XI motor domain in complex with ADP-ALF4 · an experimental structure of the same protein · chain A against A, TM-score 0.42
7DHW · Crystal structure of myosin-XI motor domain in complex with ADP-ALF4 · an experimental structure of the same protein · chain A against A, TM-score 0.42

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9LKB9
Elsewhere: UniProt Q9LKB9 · AlphaFold DB Q9LKB9

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