MolNFT v1 · #255454 · protein
AlphaFold monomer V2.0 prediction for myosin light chain kinase 2, SKELETAL/CARDIAC muscle (Q9H1R3)
Q9H1R3: “AlphaFold monomer V2.0 prediction for myosin light chain kinase 2, SKELETAL/CARDIAC muscle (Q9H1R3)”. 4 pockets (best druggability 0.75). MolNFT v1 #255454 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9H1R3
- Type
- protein
- Length
- 596 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x35cE46a4a30196447966Bd34E1e090Eb6D1bAd3f
- Molecule
- Myosin light chain kinase 2, SKELETAL/CARDIAC muscle
- UniProt
- Q9H1R3
- Pockets
- 4 · best druggability 0.75
Structure
1 distinct chain · 24% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Myosin light chain kinase 2, SKELETAL/CARDIAC muscle | protein | 596 | 24% helix, 10% strand | Q9H1R3 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 548 | 0.75 | 0.82 | 60 | empty |
| 2 | 112 | 0.51 | 0.81 | 20 | empty |
| 3 | 134 | 0.44 | 0.76 | 19 | empty |
| 4 | 69 | 0.31 | 0.74 | 15 | empty |
Compared structures
- 2LV6 · The complex between ca-calmodulin and skeletal muscle myosin light chain kinase from… · an experimental structure of the same protein · chain A against B, TM-score 0.04
- 2LV6 · The complex between Ca-Calmodulin and skeletal muscle myosin light chain kinase from… · an experimental structure of the same protein · chain A against B, TM-score 0.04
- 3KF9 · Crystal structure of the SdCen/skMLCK complex · an experimental structure of the same protein · chain A against B, TM-score 0.04
- 3KF9 · Crystal structure of the SDCEN/SKMLCK complex · an experimental structure of the same protein · chain A against B, TM-score 0.04
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9H1R3
- Elsewhere: UniProt Q9H1R3 · AlphaFold DB Q9H1R3
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