MolNFT v1 · #254743 · protein

AlphaFold monomer V2.0 prediction for diphosphomevalonate decarboxylase (Q99JF5)

Q99JF5: “AlphaFold monomer V2.0 prediction for diphosphomevalonate decarboxylase (Q99JF5)”. 1 pocket (best druggability 0.75). MolNFT v1 #254743 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q99JF5
Type: protein
Length: 401 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xbb2F1C7CB3A1eeFAc24fCa72cc627162D5413FD7
Molecule: Diphosphomevalonate decarboxylase
UniProt: Q99JF5
Pockets: 1 · best druggability 0.75

Structure

1 distinct chain · 39% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Diphosphomevalonate decarboxylase	protein	401	39% helix, 23% strand	Q99JF5

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	520	0.75	0.83	70	empty

Compared structures

3F0N · Mus Musculus Mevalonate Pyrophosphate Decarboxylase · an experimental structure of the same protein · chain A against A, TM-score 0.95
3F0N · Mus musculus mevalonate pyrophosphate decarboxylase · an experimental structure of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q99JF5
Elsewhere: UniProt Q99JF5 · AlphaFold DB Q99JF5

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