MolNFT v1 · #254673 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q8DC53)
Q8DC53: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q8DC53)”. 10 pockets (best druggability 0.73). MolNFT v1 #254673 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8DC53
- Type
- protein
- Length
- 853 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6Ed09D80e98fE15DE51C9E7a8896AbF1f2365C3e
- Molecule
- DNA mismatch repair protein muts
- UniProt
- Q8DC53
- Pockets
- 10 · best druggability 0.73
Structure
1 distinct chain · 48% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 853 | 48% helix, 19% strand | Q8DC53 |
Pockets
10 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 622 | 0.73 | 0.80 | 63 | empty |
| 2 | 450 | 0.62 | 0.76 | 31 | empty |
| 3 | 341 | 0.59 | 0.77 | 32 | empty |
| 4 | 129 | 0.43 | 0.76 | 22 | empty |
| 5 | 118 | 0.41 | 0.76 | 21 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8DC53
- Elsewhere: UniProt Q8DC53 · AlphaFold DB Q8DC53
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