MolNFT v1 · #254647 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q56215)
Q56215: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q56215)”. 8 pockets (best druggability 0.65). MolNFT v1 #254647 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q56215
- Type
- protein
- Length
- 811 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x429aA010A80A47FF4a2777bB34A2bba144d19df2
- Molecule
- DNA mismatch repair protein muts
- UniProt
- Q56215
- Pockets
- 8 · best druggability 0.65
Structure
1 distinct chain · 48% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 811 | 48% helix, 19% strand | Q56215 |
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 631 | 0.65 | 0.75 | 50 | empty |
| 2 | 410 | 0.65 | 0.78 | 31 | empty |
| 3 | 296 | 0.61 | 0.79 | 30 | empty |
| 4 | 199 | 0.48 | 0.75 | 36 | empty |
| 5 | 106 | 0.39 | 0.76 | 19 | empty |
Compared structures
- 1EWQ · Crystal structure taq muts complexed with a heteroduplex DNA at 2.2 a resolution · an experimental structure of the same protein · chain A against A, TM-score 0.93
- 1EWQ · Crystal structure taq muts complexed with a heteroduplex DNA at 2.2 a resolution · an experimental structure of the same protein · chain A against A, TM-score 0.93
- 1NNE · Crystal Structure of the MutS-ADPBeF3-DNA complex · an experimental structure of the same protein · chain A against A, TM-score 0.93
- 1NNE · Crystal structure of the muts-ADPBEF3-DNA complex · an experimental structure of the same protein · chain A against A, TM-score 0.93
- 1FW6 · Crystal structure of a taq muts-DNA-ADP ternary complex · an experimental structure of the same protein · chain A against A, TM-score 0.93
- 1FW6 · Crystal structure of a taq muts-DNA-ADP ternary complex · an experimental structure of the same protein · chain A against A, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q56215
- Elsewhere: UniProt Q56215 · AlphaFold DB Q56215
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