MolNFT v1 · #254623 · protein

AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A3CR17)

A3CR17: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A3CR17)”. 7 pockets (best druggability 0.76). MolNFT v1 #254623 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: A3CR17
Type: protein
Length: 849 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x9e5E98E011361C5888c92e2CDb7652E02Bd5C7Ed
Molecule: DNA mismatch repair protein muts
UniProt: A3CR17
Pockets: 7 · best druggability 0.76

Structure

1 distinct chain · 46% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA mismatch repair protein muts	protein	849	46% helix, 19% strand	A3CR17

Pockets

7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	810	0.76	0.80	74	empty
2	676	0.71	0.78	65	empty
3	464	0.63	0.76	33	empty
4	54	0.42	0.82	17	empty
5	111	0.37	0.74	23	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A3CR17
Elsewhere: UniProt A3CR17 · AlphaFold DB A3CR17

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