MolNFT v1 · #254619 · protein

AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (P0DC61)

P0DC61: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (P0DC61)”. 8 pockets (best druggability 0.77). MolNFT v1 #254619 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P0DC61
Type: protein
Length: 851 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xD6c8c70034505E2afFB97C831d798cF5AA67e537
Molecule: DNA mismatch repair protein muts
UniProt: P0DC61
Pockets: 8 · best druggability 0.77

Structure

1 distinct chain · 46% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA mismatch repair protein muts	protein	851	46% helix, 19% strand	P0DC61

Pockets

8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	925	0.77	0.79	95	empty
2	493	0.66	0.78	44	empty
3	200	0.50	0.77	34	empty
4	237	0.47	0.73	28	empty
5	125	0.39	0.74	24	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0DC61
Elsewhere: UniProt P0DC61 · AlphaFold DB P0DC61

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