MolNFT v1 · #254610 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q8NZ24)
Q8NZ24: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q8NZ24)”. 6 pockets (best druggability 0.79). MolNFT v1 #254610 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8NZ24
- Type
- protein
- Length
- 851 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xbb2F1C7CB3A1eeFAc24fCa72cc627162D5413FD7
- Molecule
- DNA mismatch repair protein muts
- UniProt
- Q8NZ24
- Pockets
- 6 · best druggability 0.79
Structure
1 distinct chain · 46% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 851 | 46% helix, 19% strand | Q8NZ24 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1117 | 0.79 | 0.80 | 97 | empty |
| 2 | 618 | 0.66 | 0.76 | 66 | empty |
| 3 | 163 | 0.44 | 0.75 | 25 | empty |
| 4 | 60 | 0.42 | 0.81 | 17 | empty |
| 5 | 62 | 0.38 | 0.79 | 15 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8NZ24
- Elsewhere: UniProt Q8NZ24 · AlphaFold DB Q8NZ24
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