MolNFT v1 · #254605 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q99XL8)
Q99XL8: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q99XL8)”. 7 pockets (best druggability 0.75). MolNFT v1 #254605 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q99XL8
- Type
- protein
- Length
- 851 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6Ed09D80e98fE15DE51C9E7a8896AbF1f2365C3e
- Molecule
- DNA mismatch repair protein muts
- UniProt
- Q99XL8
- Pockets
- 7 · best druggability 0.75
Structure
1 distinct chain · 46% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 851 | 46% helix, 18% strand | Q99XL8 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 705 | 0.75 | 0.80 | 74 | empty |
| 2 | 627 | 0.68 | 0.77 | 73 | empty |
| 3 | 216 | 0.54 | 0.78 | 31 | empty |
| 4 | 269 | 0.51 | 0.74 | 25 | empty |
| 5 | 159 | 0.43 | 0.74 | 27 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99XL8
- Elsewhere: UniProt Q99XL8 · AlphaFold DB Q99XL8
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