MolNFT v1 · #254561 · protein

AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A8H1T4)

A8H1T4: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A8H1T4)”. 9 pockets (best druggability 0.77). MolNFT v1 #254561 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: A8H1T4
Type: protein
Length: 859 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x9e5E98E011361C5888c92e2CDb7652E02Bd5C7Ed
Molecule: DNA mismatch repair protein muts
UniProt: A8H1T4
Pockets: 9 · best druggability 0.77

Structure

1 distinct chain · 48% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA mismatch repair protein muts	protein	859	48% helix, 18% strand	A8H1T4

Pockets

9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1196	0.77	0.79	103	empty
2	499	0.66	0.77	32	empty
3	210	0.51	0.76	26	empty
4	57	0.38	0.80	15	empty
5	78	0.36	0.76	14	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A8H1T4
Elsewhere: UniProt A8H1T4 · AlphaFold DB A8H1T4

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