MolNFT v1 · #254557 · protein

AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q086A1)

Q086A1: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q086A1)”. 8 pockets (best druggability 0.78). MolNFT v1 #254557 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q086A1
Type: protein
Length: 861 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xaa881a9f97666A01Da48Ea02eAe65Ad17eb8B4F6
Molecule: DNA mismatch repair protein muts
UniProt: Q086A1
Pockets: 8 · best druggability 0.78

Structure

1 distinct chain · 48% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA mismatch repair protein muts	protein	861	48% helix, 19% strand	Q086A1

Pockets

8 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1116	0.78	0.80	101	empty
2	488	0.65	0.77	31	empty
3	181	0.49	0.77	24	empty
4	176	0.47	0.76	26	empty
5	94	0.39	0.77	15	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q086A1
Elsewhere: UniProt Q086A1 · AlphaFold DB Q086A1

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