MolNFT v1 · #254551 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A1S4E6)
A1S4E6: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A1S4E6)”. 6 pockets (best druggability 0.79). MolNFT v1 #254551 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A1S4E6
- Type
- protein
- Length
- 854 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x78A19839AffE55Dec18D3CdEEd6CFa0e8b6FDd57
- Molecule
- DNA mismatch repair protein muts
- UniProt
- A1S4E6
- Pockets
- 6 · best druggability 0.79
Structure
1 distinct chain · 48% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 854 | 48% helix, 19% strand | A1S4E6 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1000 | 0.79 | 0.81 | 111 | empty |
| 2 | 463 | 0.64 | 0.77 | 30 | empty |
| 3 | 281 | 0.53 | 0.75 | 32 | empty |
| 4 | 120 | 0.43 | 0.77 | 20 | empty |
| 5 | 64 | 0.38 | 0.79 | 15 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A1S4E6
- Elsewhere: UniProt A1S4E6 · AlphaFold DB A1S4E6
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