MolNFT v1 · #254521 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A8EZG1)
A8EZG1: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A8EZG1)”. 9 pockets (best druggability 0.69). MolNFT v1 #254521 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A8EZG1
- Type
- protein
- Length
- 891 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5217B152D91A2206F58004ED4C9c6947a29BfCDC
- Molecule
- DNA mismatch repair protein muts
- UniProt
- A8EZG1
- Pockets
- 9 · best druggability 0.69
Structure
1 distinct chain · 51% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 891 | 51% helix, 19% strand | A8EZG1 |
Pockets
9 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 415 | 0.69 | 0.81 | 51 | empty |
| 2 | 497 | 0.67 | 0.78 | 49 | empty |
| 3 | 489 | 0.62 | 0.76 | 34 | empty |
| 4 | 292 | 0.52 | 0.74 | 33 | empty |
| 5 | 205 | 0.47 | 0.74 | 20 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A8EZG1
- Elsewhere: UniProt A8EZG1 · AlphaFold DB A8EZG1
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