MolNFT v1 · #254519 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A8GX86)
A8GX86: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A8GX86)”. 6 pockets (best druggability 0.68). MolNFT v1 #254519 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A8GX86
- Type
- protein
- Length
- 888 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x1ED4a68B4011314730adE976b56Ad4cA21b54dcD
- Molecule
- DNA mismatch repair protein muts
- UniProt
- A8GX86
- Pockets
- 6 · best druggability 0.68
Structure
1 distinct chain · 51% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 888 | 51% helix, 19% strand | A8GX86 |
Pockets
6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 566 | 0.68 | 0.78 | 56 | empty |
| 2 | 534 | 0.64 | 0.76 | 39 | empty |
| 3 | 321 | 0.62 | 0.79 | 33 | empty |
| 4 | 247 | 0.56 | 0.78 | 31 | empty |
| 5 | 62 | 0.33 | 0.76 | 12 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A8GX86
- Elsewhere: UniProt A8GX86 · AlphaFold DB A8GX86
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