MolNFT v1 · #254514 · protein

AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q21CE8)

Q21CE8: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q21CE8)”. 8 pockets (best druggability 0.79). MolNFT v1 #254514 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q21CE8
Type: protein
Length: 905 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x10F20E5FD6223F71224Fba7496Eba14cf3dd37D0
Molecule: DNA mismatch repair protein muts
UniProt: Q21CE8
Pockets: 8 · best druggability 0.79

Structure

1 distinct chain · 47% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA mismatch repair protein muts	protein	905	47% helix, 18% strand	Q21CE8

Pockets

8 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1005	0.79	0.81	104	empty
2	318	0.54	0.75	31	empty
3	204	0.46	0.74	30	empty
4	130	0.41	0.75	19	empty
5	54	0.41	0.81	16	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q21CE8
Elsewhere: UniProt Q21CE8 · AlphaFold DB Q21CE8

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