MolNFT v1 · #254509 · protein

AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q7UP05)

Q7UP05: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q7UP05)”. 7 pockets (best druggability 0.79). MolNFT v1 #254509 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q7UP05
Type: protein
Length: 891 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xf87a97E0A4bB354D834857B14296240B167cbe70
Molecule: DNA mismatch repair protein muts
UniProt: Q7UP05
Pockets: 7 · best druggability 0.79

Structure

1 distinct chain · 47% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA mismatch repair protein muts	protein	891	47% helix, 18% strand	Q7UP05

Pockets

7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	999	0.79	0.81	114	empty
2	325	0.53	0.74	42	empty
3	244	0.47	0.74	31	empty
4	221	0.47	0.74	40	empty
5	57	0.43	0.83	16	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7UP05
Elsewhere: UniProt Q7UP05 · AlphaFold DB Q7UP05

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