MolNFT v1 · #254490 · protein

AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A5W816)

A5W816: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A5W816)”. 6 pockets (best druggability 0.76). MolNFT v1 #254490 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: A5W816
Type: protein
Length: 857 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xB35df660264f41795De49C83276C108A4ba91ADE
Molecule: DNA mismatch repair protein muts
UniProt: A5W816
Pockets: 6 · best druggability 0.76

Structure

1 distinct chain · 46% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA mismatch repair protein muts	protein	857	46% helix, 19% strand	A5W816

Pockets

6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1167	0.76	0.79	101	empty
2	511	0.67	0.78	32	empty
3	271	0.54	0.76	29	empty
4	99	0.35	0.74	17	empty
5	59	0.33	0.77	17	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A5W816
Elsewhere: UniProt A5W816 · AlphaFold DB A5W816

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