MolNFT v1 · #254489 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A8F753)
A8F753: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A8F753)”. 9 pockets (best druggability 0.75). MolNFT v1 #254489 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A8F753
- Type
- protein
- Length
- 811 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5881B09f2D8e743400698633641fc1cD2Ed2BE6F
- Molecule
- DNA mismatch repair protein muts
- UniProt
- A8F753
- Pockets
- 9 · best druggability 0.75
Structure
1 distinct chain · 47% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 811 | 47% helix, 19% strand | A8F753 |
Pockets
9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 887 | 0.75 | 0.78 | 98 | empty |
| 2 | 468 | 0.60 | 0.75 | 41 | empty |
| 3 | 316 | 0.54 | 0.75 | 42 | empty |
| 4 | 96 | 0.37 | 0.75 | 21 | empty |
| 5 | 76 | 0.36 | 0.76 | 19 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A8F753
- Elsewhere: UniProt A8F753 · AlphaFold DB A8F753
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