MolNFT v1 · #254479 · protein

AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q46IE5)

Q46IE5: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q46IE5)”. 9 pockets (best druggability 0.75). MolNFT v1 #254479 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q46IE5
Type: protein
Length: 926 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x7782F4817b37743d738e9aF842bf74bd50f2015E
Molecule: DNA mismatch repair protein muts
UniProt: Q46IE5
Pockets: 9 · best druggability 0.75

Structure

1 distinct chain · 42% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA mismatch repair protein muts	protein	926	42% helix, 18% strand	Q46IE5

Pockets

9 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	919	0.75	0.79	88	empty
2	815	0.71	0.77	59	empty
3	191	0.47	0.75	36	empty
4	130	0.40	0.75	24	empty
5	143	0.39	0.73	21	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q46IE5
Elsewhere: UniProt Q46IE5 · AlphaFold DB Q46IE5

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