MolNFT v1 · #254456 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (P57972)
P57972: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (P57972)”. 8 pockets (best druggability 0.76). MolNFT v1 #254456 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P57972
- Type
- protein
- Length
- 860 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7012c0b45c68a2c067644b9d3e5DDa06892c6957
- Molecule
- DNA mismatch repair protein muts
- UniProt
- P57972
- Pockets
- 8 · best druggability 0.76
Structure
1 distinct chain · 49% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 860 | 49% helix, 19% strand | P57972 |
Pockets
8 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 887 | 0.76 | 0.79 | 92 | empty |
| 2 | 486 | 0.66 | 0.77 | 33 | empty |
| 3 | 422 | 0.61 | 0.76 | 34 | empty |
| 4 | 360 | 0.56 | 0.75 | 38 | empty |
| 5 | 115 | 0.41 | 0.76 | 19 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P57972
- Elsewhere: UniProt P57972 · AlphaFold DB P57972
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