MolNFT v1 · #254420 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q46CE2)
Q46CE2: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q46CE2)”. 8 pockets (best druggability 0.72). MolNFT v1 #254420 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q46CE2
- Type
- protein
- Length
- 900 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x79a905d858Ce72991FD6E7a9C6498620f42E146D
- Molecule
- DNA mismatch repair protein muts
- UniProt
- Q46CE2
- Pockets
- 8 · best druggability 0.72
Structure
1 distinct chain · 46% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 900 | 46% helix, 18% strand | Q46CE2 |
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 795 | 0.72 | 0.77 | 79 | empty |
| 2 | 486 | 0.70 | 0.80 | 38 | empty |
| 3 | 615 | 0.68 | 0.77 | 46 | empty |
| 4 | 64 | 0.34 | 0.76 | 13 | empty |
| 5 | 68 | 0.33 | 0.76 | 14 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q46CE2
- Elsewhere: UniProt Q46CE2 · AlphaFold DB Q46CE2
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