MolNFT v1 · #254419 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q8TTB4)
Q8TTB4: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q8TTB4)”. 7 pockets (best druggability 0.74). MolNFT v1 #254419 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8TTB4
- Type
- protein
- Length
- 900 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x3aC9742557B5a280CCBE5c6e54942967FB5201eD
- Molecule
- DNA mismatch repair protein muts
- UniProt
- Q8TTB4
- Pockets
- 7 · best druggability 0.74
Structure
1 distinct chain · 47% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 900 | 47% helix, 19% strand | Q8TTB4 |
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1038 | 0.74 | 0.77 | 108 | empty |
| 2 | 452 | 0.69 | 0.80 | 38 | empty |
| 3 | 496 | 0.66 | 0.78 | 39 | empty |
| 4 | 124 | 0.40 | 0.75 | 21 | empty |
| 5 | 76 | 0.38 | 0.77 | 13 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8TTB4
- Elsewhere: UniProt Q8TTB4 · AlphaFold DB Q8TTB4
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