MolNFT v1 · #254394 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q04RT2)
Q04RT2: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q04RT2)”. 10 pockets (best druggability 0.67). MolNFT v1 #254394 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q04RT2
- Type
- protein
- Length
- 848 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xCACEF60BdA4Ce8E2d7423EAb841647271C1514e8
- Molecule
- DNA mismatch repair protein muts
- UniProt
- Q04RT2
- Pockets
- 10 · best druggability 0.67
Structure
1 distinct chain · 45% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 848 | 45% helix, 19% strand | Q04RT2 |
Pockets
10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 131 | 0.67 | 0.89 | 27 | empty |
| 2 | 387 | 0.64 | 0.78 | 35 | empty |
| 3 | 352 | 0.55 | 0.74 | 42 | empty |
| 4 | 219 | 0.55 | 0.78 | 21 | empty |
| 5 | 165 | 0.52 | 0.79 | 29 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q04RT2
- Elsewhere: UniProt Q04RT2 · AlphaFold DB Q04RT2
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