MolNFT v1 · #254391 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A5ICW2)
A5ICW2: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A5ICW2)”. 9 pockets (best druggability 0.72). MolNFT v1 #254391 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A5ICW2
- Type
- protein
- Length
- 846 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xBeB220F0B5b0C48F46B5DDd3E3b071BC0827f8D6
- Molecule
- DNA mismatch repair protein muts
- UniProt
- A5ICW2
- Pockets
- 9 · best druggability 0.72
Structure
1 distinct chain · 48% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 846 | 48% helix, 19% strand | A5ICW2 |
Pockets
9 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 120 | 0.72 | 0.93 | 23 | empty |
| 2 | 445 | 0.67 | 0.79 | 48 | empty |
| 3 | 493 | 0.64 | 0.76 | 44 | empty |
| 4 | 446 | 0.63 | 0.77 | 42 | empty |
| 5 | 147 | 0.44 | 0.76 | 21 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A5ICW2
- Elsewhere: UniProt A5ICW2 · AlphaFold DB A5ICW2
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