MolNFT v1 · #254383 · protein

AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A2RP10)

A2RP10: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A2RP10)”. 9 pockets (best druggability 0.71). MolNFT v1 #254383 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: A2RP10
Type: protein
Length: 840 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x1d5DCa9830f6Ca963D9Bb5f9787E2AAfa85A53eA
Molecule: DNA mismatch repair protein muts
UniProt: A2RP10
Pockets: 9 · best druggability 0.71

Structure

1 distinct chain · 48% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA mismatch repair protein muts	protein	840	48% helix, 19% strand	A2RP10

Pockets

9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	475	0.71	0.81	57	empty
2	591	0.64	0.75	55	empty
3	330	0.57	0.76	29	empty
4	107	0.43	0.77	20	empty
5	78	0.39	0.78	13	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A2RP10
Elsewhere: UniProt A2RP10 · AlphaFold DB A2RP10

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