MolNFT v1 · #254356 · protein

AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q4QML2)

Q4QML2: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q4QML2)”. 8 pockets (best druggability 0.73). MolNFT v1 #254356 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q4QML2
Type: protein
Length: 861 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x040D7800282366e252C6117b672856B70940877d
Molecule: DNA mismatch repair protein muts
UniProt: Q4QML2
Pockets: 8 · best druggability 0.73

Structure

1 distinct chain · 49% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA mismatch repair protein muts	protein	861	49% helix, 19% strand	Q4QML2

Pockets

8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	580	0.73	0.80	65	empty
2	498	0.70	0.81	50	empty
3	515	0.66	0.77	32	empty
4	88	0.44	0.79	19	empty
5	61	0.41	0.81	15	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q4QML2
Elsewhere: UniProt Q4QML2 · AlphaFold DB Q4QML2

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