MolNFT v1 · #254336 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q14GB1)
Q14GB1: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q14GB1)”. 9 pockets (best druggability 0.75). MolNFT v1 #254336 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q14GB1
- Type
- protein
- Length
- 857 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xf84a1a54d1fa266310201FB7c6d2D02d2C25C526
- Molecule
- DNA mismatch repair protein muts
- UniProt
- Q14GB1
- Pockets
- 9 · best druggability 0.75
Structure
1 distinct chain · 49% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 857 | 49% helix, 19% strand | Q14GB1 |
Pockets
9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 871 | 0.75 | 0.79 | 91 | empty |
| 2 | 429 | 0.64 | 0.77 | 36 | empty |
| 3 | 215 | 0.53 | 0.77 | 22 | empty |
| 4 | 171 | 0.50 | 0.77 | 26 | empty |
| 5 | 157 | 0.43 | 0.74 | 17 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q14GB1
- Elsewhere: UniProt Q14GB1 · AlphaFold DB Q14GB1
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