MolNFT v1 · #254328 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (B7LWH8)
B7LWH8: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (B7LWH8)”. 8 pockets (best druggability 0.79). MolNFT v1 #254328 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- B7LWH8
- Type
- protein
- Length
- 853 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xABe0e3272975F494B3518B81D67f49E88D733e3B
- Molecule
- DNA mismatch repair protein muts
- UniProt
- B7LWH8
- Pockets
- 8 · best druggability 0.79
Structure
1 distinct chain · 47% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 853 | 47% helix, 19% strand | B7LWH8 |
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1085 | 0.79 | 0.80 | 110 | empty |
| 2 | 461 | 0.65 | 0.78 | 37 | empty |
| 3 | 75 | 0.58 | 0.88 | 20 | empty |
| 4 | 160 | 0.49 | 0.77 | 32 | empty |
| 5 | 167 | 0.46 | 0.75 | 23 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B7LWH8
- Elsewhere: UniProt B7LWH8 · AlphaFold DB B7LWH8
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