MolNFT v1 · #254324 · protein

AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A4WDU5)

A4WDU5: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A4WDU5)”. 7 pockets (best druggability 0.79). MolNFT v1 #254324 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: A4WDU5
Type: protein
Length: 853 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x79a905d858Ce72991FD6E7a9C6498620f42E146D
Molecule: DNA mismatch repair protein muts
UniProt: A4WDU5
Pockets: 7 · best druggability 0.79

Structure

1 distinct chain · 47% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA mismatch repair protein muts	protein	853	47% helix, 19% strand	A4WDU5

Pockets

7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1049	0.79	0.81	108	empty
2	471	0.64	0.77	31	empty
3	123	0.47	0.79	19	empty
4	95	0.40	0.77	21	empty
5	95	0.39	0.76	14	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A4WDU5
Elsewhere: UniProt A4WDU5 · AlphaFold DB A4WDU5

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