MolNFT v1 · #254321 · protein

AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q5FHE8)

Q5FHE8: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q5FHE8)”. 4 pockets (best druggability 0.79). MolNFT v1 #254321 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q5FHE8
Type: protein
Length: 804 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xd1A2963012bEcbC7A8f505464439Ab678C48936f
Molecule: DNA mismatch repair protein muts
UniProt: Q5FHE8
Pockets: 4 · best druggability 0.79

Structure

1 distinct chain · 48% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA mismatch repair protein muts	protein	804	48% helix, 20% strand	Q5FHE8

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1091	0.79	0.80	124	empty
2	484	0.62	0.76	42	empty
3	92	0.39	0.76	12	empty
4	93	0.38	0.76	17	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5FHE8
Elsewhere: UniProt Q5FHE8 · AlphaFold DB Q5FHE8

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.