MolNFT v1 · #254317 · protein

AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q1R7W4)

Q1R7W4: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q1R7W4)”. 8 pockets (best druggability 0.78). MolNFT v1 #254317 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q1R7W4
Type: protein
Length: 853 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xd10960F956646DE8b64d3598984c91C2d5Af3D7b
Molecule: DNA mismatch repair protein muts
UniProt: Q1R7W4
Pockets: 8 · best druggability 0.78

Structure

1 distinct chain · 48% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA mismatch repair protein muts	protein	853	48% helix, 19% strand	Q1R7W4

Pockets

8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	735	0.78	0.83	83	empty
2	479	0.65	0.77	38	empty
3	342	0.64	0.79	34	empty
4	145	0.47	0.78	28	empty
5	110	0.44	0.78	18	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q1R7W4
Elsewhere: UniProt Q1R7W4 · AlphaFold DB Q1R7W4

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