MolNFT v1 · #254314 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (B7N6W4)
B7N6W4: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (B7N6W4)”. 7 pockets (best druggability 0.80). MolNFT v1 #254314 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- B7N6W4
- Type
- protein
- Length
- 853 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xe68A5109F149B286F3fb6Fbb333E888F4332beFE
- Molecule
- DNA mismatch repair protein muts
- UniProt
- B7N6W4
- Pockets
- 7 · best druggability 0.80
Structure
1 distinct chain · 48% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 853 | 48% helix, 19% strand | B7N6W4 |
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1150 | 0.80 | 0.81 | 116 | empty |
| 2 | 463 | 0.65 | 0.78 | 37 | empty |
| 3 | 280 | 0.54 | 0.76 | 33 | empty |
| 4 | 98 | 0.42 | 0.78 | 23 | empty |
| 5 | 87 | 0.37 | 0.76 | 14 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B7N6W4
- Elsewhere: UniProt B7N6W4 · AlphaFold DB B7N6W4
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