GL1X · GenesisL1 explorer

MolNFT v1 · #254296 · protein

AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A8LPD4)

A8LPD4: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (A8LPD4)”. 6 pockets (best druggability 0.80). MolNFT v1 #254296 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
A8LPD4
Type
protein
Length
877 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xC26902D5844E7F183370B5392D064CE0247305cd
Molecule
DNA mismatch repair protein muts
UniProt
A8LPD4
Pockets
6 · best druggability 0.80

Structure

1 distinct chain · 49% helix, 19% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA mismatch repair protein mutsprotein87749% helix, 19% strandA8LPD4

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
19880.800.81104empty
24590.620.7641empty
3980.460.8017empty
41350.410.7523empty
5800.390.7819empty

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