MolNFT v1 · #254288 · protein
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (B8J008)
B8J008: “AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (B8J008)”. 8 pockets (best druggability 0.73). MolNFT v1 #254288 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- B8J008
- Type
- protein
- Length
- 927 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x28fdd3B14dbA8880a8e7963Eb017057f4385ECCC
- Molecule
- DNA mismatch repair protein muts
- UniProt
- B8J008
- Pockets
- 8 · best druggability 0.73
Structure
1 distinct chain · 44% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein muts | protein | 927 | 44% helix, 17% strand | B8J008 |
Pockets
8 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 790 | 0.73 | 0.79 | 59 | empty |
| 2 | 501 | 0.70 | 0.80 | 46 | empty |
| 3 | 457 | 0.62 | 0.76 | 35 | empty |
| 4 | 281 | 0.52 | 0.75 | 39 | empty |
| 5 | 97 | 0.48 | 0.80 | 18 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B8J008
- Elsewhere: UniProt B8J008 · AlphaFold DB B8J008
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